This medicated shampoo pairs 2.3% chlorhexidine gluconate with 1% ketoconazole to target skin conditions responsive to these two antimicrobial agents. It is formulated with S-I-S Skin Innovative Science technology, including glycotechnology and defensin-supporting ingredients, intended to limit microbial adhesion to the skin and support the coat's natural defenses. The low-lather cleanser degreases, descales, and helps neutralize unpleasant odors while leaving a mild floral scent on the coat. To use, the coat is wetted with warm water, shampoo is worked into a lather and left in contact with the skin for five to ten minutes, then rinsed thoroughly. Bathing frequency typically starts at two to three times weekly before tapering to once weekly, following a veterinarian's directions. This product requires a prescription from a licensed veterinarian prior to purchase.