These soft, chewable dental treats are formulated with A.N ProDen, a natural kelp ingredient sustainably harvested from cold coastal waters, along with brewers dried yeast, canola oil, dried potato product and other ingredients that give the chews their soft texture. They are intended for large and giant breed dogs weighing more than 51 pounds and are designed to be given once daily as part of an ongoing oral care routine. The kelp-based formula is intended to help control plaque and tartar buildup on the teeth and to support fresher breath, with changes typically noted after several weeks of consistent use. The chews are manufactured in the United States. Fresh water should be available at all times when feeding these chews, and they should be stored in a cool, dry place. Because kelp naturally contains iodine, caution is advised when feeding these chews to dogs with thyroid conditions.