EFFITIX PLUS Topical Solution for Dogs contains the active ingredients fipronil, permethrin, and pyriproxyfen which control infestations of fleas (including flea eggs, maggot-like flea larvea and pupae), ticks and lice; repel against biting flies, and repel and kill mosquitoes. Quick-drying, non-greasy, EFFITIX PLUS Topical Solution for Dogs remains effective after bathing, shampooing, water immersion or sunlight exposure. For easy and convenient application, EFFITIX PLUS Topical Solution for Dogs is available for puppies and dogs 8 weeks old or older and in 5 dose sizes for dogs from 5 to 132 lbs.