API Melafix is a botanical liquid treatment formulated with melaleuca (tea tree) extract for use in freshwater and saltwater aquariums. It is added directly to tank water using the measured dosing cap included on the bottle, with no mixing or assembly required. The formula is designed to leave the biological filter, water pH, and water clarity unaffected during dosing. It is labeled as safe for use in reef aquariums, with live plants, and around a range of fish species when directions are followed. A typical treatment cycle involves daily dosing over a period of days followed by a partial water change, and the product can also be used as a precaution when acclimating newly purchased fish. Some surface foaming can occur during treatment, which is considered a normal reaction to the formula rather than a sign of a problem.